兔腹膜组织生成15-羟基-5,8,11,13-二十碳四烯酸（15-HETE）
15-Hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) formation by rabbit peritoneal tissue.
作者信息
Claeys M, Coene M C, Herman A G, Van der Planken M, Jouvenaz G H, Nugteren D H
出版信息
Agents Actions. 1981 Dec;11(6-7):589-91. doi: 10.1007/BF01978754.
PMID:6803536
Abstract
The capacity of rabbit peritoneal tissue to produce lipoxygenase metabolites from exogenous arachidonic acid has been studied. The lipoxygenase pathway of arachidonic acid in this tissue is mainly directed to 15-HETE. Preliminary experiments with peritoneal macrophages indicate that these cells, just like PMN leukocytes, may contribute to the 15-HETE formation observed in peritoneal tissue.
摘要
已对兔腹膜组织从外源性花生四烯酸产生脂氧合酶代谢产物的能力进行了研究。该组织中花生四烯酸的脂氧合酶途径主要导向15-羟基二十碳四烯酸（15-HETE）。腹膜巨噬细胞的初步实验表明，这些细胞与中性粒细胞一样，可能促成了在腹膜组织中观察到的15-HETE的形成。
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