Akhras F, Upward J, Stott R, Jackson G
Br Med J (Clin Res Ed). 1982 May 1;284(6325):1293-4. doi: 10.1136/bmj.284.6325.1293.
In a prospective study 61 patients aged 55 years or less with uncomplicated myocardial infarction underwent treadmill stress testing at two weeks and coronary angiography at six weeks after infarction. Of the 44 patients who had a positive stress test, 43 had additional severe coronary artery disease confirmed by coronary angiography. Of the 17 patients who had a negative stress test for additional disease, coronary angiography identified only single-vessel disease in the infarct area in 15. The sensitivity of the stress test was 95% and the specificity 94%, though the number of patients in the study was small. Thus, exercise testing has considerable potential for the early identification of multiple-vessel disease in patients with uncomplicated myocardial infarction.
在一项前瞻性研究中,61例年龄在55岁及以下的无并发症心肌梗死患者在梗死后两周接受了平板运动试验,并在六周时接受了冠状动脉造影。在44例运动试验阳性的患者中,43例经冠状动脉造影证实有额外的严重冠状动脉疾病。在17例运动试验阴性以排除其他疾病的患者中,冠状动脉造影显示15例仅在梗死区域有单支血管病变。尽管该研究中的患者数量较少,但运动试验的敏感性为95%,特异性为94%。因此,运动试验在早期识别无并发症心肌梗死患者的多支血管病变方面具有相当大的潜力。