[一种硝基呋喃衍生物对质粒扩散的抑制作用]
[Inhibition of the diffusion of plasmids by a nitrofuran derivative].
作者信息
Michel-Briand Y, Laporte J M
出版信息
C R Seances Acad Sci III. 1982 Feb 1;294(5):249-52.
PMID:6804030
Abstract
Antibiotic resistance plasmids PR4, R6K, and RGN238 can transfer between Escherichia coli cells by conjugation (transfer frequency: 3 to 3.5 x 10(-4)). Nifurzide, a nitrofuran derivative, greatly depresses plasmid transfer at concentrations (59 microM) which do not affect cell viability.
摘要
抗生素抗性质粒PR4、R6K和RGN238可通过接合在大肠杆菌细胞间转移（转移频率：3至3.5×10⁻⁴）。硝呋齐特，一种硝基呋喃衍生物，在不影响细胞活力的浓度（59微摩尔）下可极大地抑制质粒转移。
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