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[急性高热猫呼吸与循环变化的比较特征]

[Comparative characteristics of respiratory and circulatory changes in acutely hyperthermic cats].

作者信息

Tashliev V A, Dvoretskiĭ D P

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1982 Mar;68(3):405-10.

PMID:6804281
Abstract

During three-hour heating, cats revealed two phases of changes in respiratory and circulatory systems: the compensatory phase corresponding to a moderate hyperthermia (rectal temperature 39.4 +/- 0.17 degrees C) and the decompensatory one developing at rectal temperature over 39.9 +/- 0.15 degrees C. In the first phase the alveolar ventilation, oxygen consumption, excretion of CO2 and one-minute respiratory volume increase to the same extent as the one-minute blood volume, the increased metabolism and heat production occurring against the background of the blood acid-alkaline homeostasis. In the second phase an imbalance of functions of respiratory and circulatory systems occurs leading to a decrease in the one-minute blood volume, an increase in the alveolar ventilation-lung blood flow ratio, a sharp drop of the pulmonary gas exchange and a respiratory alkalosis.

摘要

在三小时的加热过程中,猫的呼吸和循环系统出现了两个变化阶段:对应于中度体温过高(直肠温度39.4±0.17摄氏度)的代偿阶段,以及直肠温度超过39.9±0.15摄氏度时出现的失代偿阶段。在第一阶段,肺泡通气、氧气消耗、二氧化碳排泄和每分钟呼吸量的增加幅度与每分钟血容量相同,代谢和产热增加是在血液酸碱平衡的背景下发生的。在第二阶段,呼吸和循环系统功能出现失衡,导致每分钟血容量减少、肺泡通气与肺血流量比值增加、肺气体交换急剧下降以及呼吸性碱中毒。

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