McGuckin M B, Thorpe R J, Koch K M, Alavi A, Staum M, Abrutyn E
Am J Epidemiol. 1982 May;115(5):785-93. doi: 10.1093/oxfordjournals.aje.a113360.
In December, 1978, an investigation was undertaken to determine the source of infection in five patients in one hospital with hospital-associated bacteremia due to Achromobacter xylosoxidans. Review of their records showed that each had a diagnostic tracer procedure preceding the bacteremia and that no other procedures were common to all. Further investigation revealed that patients from three other hospitals were studied using diagnostic tracer materials from the index hospital. Five patients with confirmed A. xylosoxidans bacteremia and four suspected cases were identified in these hospitals, and all had a scan before the bacteremia was detected. No other A. xylosoxidans isolates were identified in any of the hospitals in the preceding two years. Although not confirmed, the source appeared to be stored non-bacteriostatic saline. Effective control measures included a sterility testing program and use of pre-packaged single dose vials of saline. Diagnostic tracer studies should be added to the list of procedures known to cause hospital-acquired bacteremias.
1978年12月，开展了一项调查，以确定某医院5例因木糖氧化无色杆菌导致医院相关菌血症患者的感染源。查阅他们的病历发现，每位患者在菌血症发生前都接受了诊断性示踪程序，且所有患者并无其他共同的程序。进一步调查显示，其他三家医院的患者使用了来自该索引医院的诊断性示踪材料进行研究。在这些医院中，确认了5例木糖氧化无色杆菌菌血症患者和4例疑似病例，且所有患者在菌血症被检测出之前都进行了扫描。在之前两年中，任何一家医院均未鉴定出其他木糖氧化无色杆菌分离株。尽管未经证实，但感染源似乎是储存的非抑菌生理盐水。有效的控制措施包括无菌检测程序以及使用预包装的单剂量瓶装生理盐水。诊断性示踪研究应被列入已知可导致医院获得性菌血症的程序清单中。
