Scott J M, McLauchlan J, Smylie H G
Br Med J (Clin Res Ed). 1982 May 29;284(6329):1594-6. doi: 10.1136/bmj.284.6329.1594.
A prospective controlled trial was carried out to assess the effect of using a wound isolator on reducing postoperative infection. A total of 291 patients undergoing hip pinning for fractures of the neck of femur entered the trial and were allocated at random to have their wound contained in a wound isolator (study group) or dressed with a standard gamma-irradiated adhesive dressing (control group). The bacteriological flora of the patient was monitored before, during, and after operation and that of the ward before and after. No significant difference was found in the flora of the wards in which the patients were nursed. On several occasions the source of the infective organism was traced to the ward but never to the theatre. The isolator prevented direct contamination and airborne cross-infection of the wound and appreciably reduced the rate of infection.
进行了一项前瞻性对照试验，以评估使用伤口隔离器对减少术后感染的效果。共有291例因股骨颈骨折接受髋部固定术的患者进入试验，并被随机分配，使其伤口置于伤口隔离器中（研究组）或用标准的γ射线辐照粘性敷料包扎（对照组）。在手术前、手术期间和手术后监测患者的细菌菌群，以及病房手术前后的细菌菌群。在护理患者的病房菌群中未发现显著差异。有几次感染源追溯到病房，但从未追溯到手术室。隔离器可防止伤口的直接污染和空气传播的交叉感染，并显著降低感染率。
