Kinane D F, Blackwell C C, Brettle R P, Weir D M, Winstanley F P, Elton R A
Br Med J (Clin Res Ed). 1982 Jul 3;285(6334):7-9. doi: 10.1136/bmj.285.6334.7.
ABO blood group and secretor state was determined in 319 women with recurrent urinary tract infection and compared with those of a control group of 334 women of similar age ranges. Women of blood groups B and AB who are non-secretors of blood group substances showed a significant relative risk of recurrent urinary tract infection of 3.12 (95% confidence limits, 1.49 and 6.52) in comparison with other types. This appears to be a genuine example of synergy in which absence of anti-B isohaemagglutinin and secretor substances combines to give an increased risk of recurrent urinary tract infection. Determination of blood group and secretor state may provide additional information in identifying those at risk.
对319名复发性尿路感染女性进行了ABO血型和分泌状态测定,并与334名年龄范围相似的女性对照组进行了比较。血型为B型和AB型且不分泌血型物质的女性,与其他类型相比,复发性尿路感染的相对风险显著增加,为3.12(95%置信区间为1.49至6.52)。这似乎是协同作用的一个真实例子,即缺乏抗B同种血凝素和分泌物质共同导致复发性尿路感染风险增加。测定血型和分泌状态可能为识别高危人群提供额外信息。