氯丙嗪对枯草芽孢杆菌转化的影响。
The effect of chlorpromazine on transformation in Bacillus subtilis.
作者信息
Mooibroek H, Venema G
出版信息
Mol Gen Genet. 1982;185(1):165-8. doi: 10.1007/BF00333808.
PMID:6806562
Abstract
In the presence of the widely used tranquilizer, chlorpromazine, transforming DNA of Bacillus subtilis is photoinactivated by long-wave ultraviolet light. The loss of biological activity is predominantly caused by lack of binding of the DNA to recipient cells and the introduction of single-strand breaks in the treated DNA.
摘要
在广泛使用的镇静剂氯丙嗪存在的情况下，枯草芽孢杆菌的转化DNA会被长波紫外线光灭活。生物活性的丧失主要是由于DNA与受体细胞的结合缺失以及处理后的DNA中出现单链断裂。
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