Mooibroek H, Venema G
Mol Gen Genet. 1982;185(1):165-8. doi: 10.1007/BF00333808.
In the presence of the widely used tranquilizer, chlorpromazine, transforming DNA of Bacillus subtilis is photoinactivated by long-wave ultraviolet light. The loss of biological activity is predominantly caused by lack of binding of the DNA to recipient cells and the introduction of single-strand breaks in the treated DNA.
在广泛使用的镇静剂氯丙嗪存在的情况下,枯草芽孢杆菌的转化DNA会被长波紫外线光灭活。生物活性的丧失主要是由于DNA与受体细胞的结合缺失以及处理后的DNA中出现单链断裂。