氯丙嗪对枯草芽孢杆菌转化的影响。
The effect of chlorpromazine on transformation in Bacillus subtilis.
作者信息
Mooibroek H, Venema G
出版信息
Mol Gen Genet. 1982;185(1):165-8. doi: 10.1007/BF00333808.
PMID:6806562
Abstract
In the presence of the widely used tranquilizer, chlorpromazine, transforming DNA of Bacillus subtilis is photoinactivated by long-wave ultraviolet light. The loss of biological activity is predominantly caused by lack of binding of the DNA to recipient cells and the introduction of single-strand breaks in the treated DNA.
摘要
在广泛使用的镇静剂氯丙嗪存在的情况下，枯草芽孢杆菌的转化DNA会被长波紫外线光灭活。生物活性的丧失主要是由于DNA与受体细胞的结合缺失以及处理后的DNA中出现单链断裂。
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Inactivation of transforming Bacillus subtilis deoxyribonucleic acid by monoadducts of 4,5',8-trimethylpsoralen.4,5',8-三甲基补骨脂素单加合物对转化型枯草芽孢杆菌脱氧核糖核酸的灭活作用
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