Olsen O A, Green M M
Mutat Res. 1982 Feb 22;92(1-2):107-15. doi: 10.1016/0027-5107(82)90214-7.
Genetic tests reported here demonstrate that among the DEB-induced mutants on 2 X-chromosome loci, viz. y and w, at a minimum, one-third are chromosome deletions. Among 11 MMS-sensitive mutants tested, 9 are also somatically sensitive to DEB. In addition direct genetic tests established that the capacity to repair DEB damage induced in sperm is impaired in females homozygous for 2 mutagen-sensitive mutants. By inference the same is also the case in females homozygous for 3 other mutagen-sensitive mutants.
此处报道的基因测试表明，在由二乙基亚硝胺（DEB）诱导产生的位于两条X染色体位点（即y和w）上的突变体中，至少有三分之一是染色体缺失。在测试的11个对甲基磺酸甲酯（MMS）敏感的突变体中，有9个对DEB也表现出体细胞敏感性。此外，直接的基因测试证实，对于两个对诱变剂敏感的突变体纯合的雌性个体，其修复精子中由DEB诱导损伤的能力受损。由此推断，对于其他三个对诱变剂敏感的突变体纯合的雌性个体，情况也是如此。
