Furuhashi N, Fukaya T, Kono H, Tachibana Y, Shinkawa O, Takahashi T
Gynecol Obstet Invest. 1982;13(4):241-8. doi: 10.1159/000299525.
Luteinizing hormone-human chorionic gonadotropin (LH-hCG), follicle-stimulating hormone(FSH), beta-human chorionic gonadotropin (beta-hCG), estradiol, cortisol and testosterone levels were determined in cord venous serum and the correlation of birth weights with those hormone levels was investigated in 32 male and 35 female fetuses. There were significant negative correlations between LH-hCG or FSH levels and birth weights in the male fetus. Also there was a significant positive correlation between LH-hCG levels and birth weights in the female fetus. This data suggests that there is a sex difference during the development of the pituitary-gonadal axis.
在32例男性胎儿和35例女性胎儿中,测定了脐静脉血清中的促黄体生成素-人绒毛膜促性腺激素(LH-hCG)、促卵泡激素(FSH)、β-人绒毛膜促性腺激素(β-hCG)、雌二醇、皮质醇和睾酮水平,并研究了出生体重与这些激素水平之间的相关性。在男性胎儿中,LH-hCG或FSH水平与出生体重之间存在显著的负相关。在女性胎儿中,LH-hCG水平与出生体重之间也存在显著的正相关。该数据表明,垂体-性腺轴发育过程中存在性别差异。