Grzelińska E, Bartkowiak A, Bartosz G, Leyko W
Int J Radiat Biol Relat Stud Phys Chem Med. 1982 May;41(5):473-81. doi: 10.1080/09553008214550551.
Thiourea, and .OH scavenger, reduced the gamma-radiation-induced changes in the rigidity of erythrocyte membrane lipids, the state of membrane proteins, and lipid peroxidation. Several .OH scavengers, but not superoxide dismutase, also inhibited the radiation-induced acceleration of the transport of a hydrophilic non-electrolyte spin label TEMPOL across the erythrocyte membrane. The effects of scavengers were usually biphasic with a maximum of the protective effect. Higher concentrations of the scavengers were less effective, as in the case of radioprotection of erythrocytes to haemolysis studied previously.
硫脲，一种羟基清除剂，可减少γ辐射诱导的红细胞膜脂质刚性、膜蛋白状态和脂质过氧化的变化。几种羟基清除剂，而非超氧化物歧化酶，也抑制了辐射诱导的亲水性非电解质自旋标记物TEMPOL跨红细胞膜转运的加速。清除剂的作用通常呈双相，具有最大保护作用。清除剂浓度越高效果越差，这与之前研究的红细胞抗溶血辐射防护情况相同。
