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长期经喉插管后气管黏膜损伤的扫描电子显微镜研究(作者译)

[A scanning electron microscopic study of the tracheal mucosa damage after long-term translaryngeal intubation (author's transl)].

作者信息

Richter H G

出版信息

Laryngol Rhinol Otol (Stuttg). 1982 Feb;61(2):90-2.

PMID:6808271
Abstract

Tracheal mucosa tissue obtained by tracheotomy from 23 patients who had been intubated between 4 to 20 days was examined in the scanning electron microscope. In spite of different intubation periods almost identical tissue defects with extensive areas of epithelial degeneration reaching as far as the basal lamina were found. In contrast, patients with short-term intubation, i.e. during intubation anaesthesia, showed no mucosal changes in the areas studied. The expected damage in the lower trachea caused by the cuff of the intubation tube is described and the dangers of prolonged intubation are discussed.

摘要

对23例插管4至20天的患者,通过气管切开术获取气管黏膜组织,进行扫描电子显微镜检查。尽管插管时间不同,但发现几乎相同的组织缺损,上皮变性广泛区域延伸至基底层。相比之下,短期插管患者,即在插管麻醉期间,在所研究区域未显示黏膜变化。描述了插管导管的袖带对气管下段造成的预期损伤,并讨论了长时间插管的危险性。

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