Ono K, Satoh Y
Acta Histochem. 1982;70(1):36-42. doi: 10.1016/s0065-1281(82)80095-0.
A study was made of ultrastructural localization of acid phosphatase activity in the large intestinal mucosa of postnatal and adult rats. In rats 1 to 5 days old, phosphatase activity was observed on the microvillous membrane, the lateral cell membrane, the Golgi apparatus, the GERL of Novikoff (1963), the tubulo-vacuolar system, and on the supranuclear vacuole of the principal cells of the cecum and the ascending colon. In 30-day-old adult rats acid phosphatase activity, was noted on the GERL and the lysosomes of the principal cells in the cecum and the ascending colon. In all rats, young and adult, acid phosphatase activity was found only on the lysosomes and the GERL of the principal cells of the descending colon. Therefore, it was concluded that the acid phosphatase-containing tubulo-vacuolar system and the supranuclear vacuole in the surface principal cells of the proximal part of the large intestine of suckling rats may possess a strong phagolysosomal function as well as having an absorption capacity the same as ileal cells of suckling rats (Ono and Satoh 1981).
对新生大鼠和成年大鼠大肠黏膜中酸性磷酸酶活性的超微结构定位进行了研究。在1至5日龄的大鼠中，在微绒毛膜、侧细胞膜、高尔基体、诺维科夫（1963年）的GERL、管状-泡状系统以及盲肠和升结肠主细胞的核上液泡中观察到磷酸酶活性。在30日龄的成年大鼠中，在盲肠和升结肠主细胞的GERL和溶酶体上发现了酸性磷酸酶活性。在所有年轻和成年大鼠中，仅在降结肠主细胞的溶酶体和GERL上发现了酸性磷酸酶活性。因此，得出结论，乳鼠大肠近端表面主细胞中含酸性磷酸酶的管状-泡状系统和核上液泡可能具有很强的吞噬溶酶体功能，以及与乳鼠回肠细胞相同的吸收能力（小野和佐藤，1981年）。
