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[儿童期部分性癫痫——演变及预后因素(作者译)]

[The partial epilepsies in childhood--evolution and prognosis factors (author's transl)].

作者信息

Roger J, Dravet C, Menendez P, Bureau M

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):431-7. doi: 10.1016/s0370-4475(81)80082-2.

Abstract

The authors have studied 119 cases of partial epilepsies, selected from the patients treated in the Centre Saint-Paul between 1966 and 1970 according to the following criteria: seizures beginning before the age of 12; electro-clinical evolution known about for at least 5 years (mean duration: 13 years 3 months). The cases are separated in 4 groups according to the severity of epilepsy: (1) complete recovery and withdrawal of treatment; (2) no seizure with treatment; (3) persisting seizures with treatment; (4) frequent and severe seizures with treatment. The severe epilepsies are characterized by an early commencement of fits (before 3 years), associated symptoms of encephalopathy, lack of familial antecedents, association of several types of seizures, or the existence of a particular critical semiology (either complex partial motor seizures, or succession of simple motor and complex semiology, sudden fall, or reflex triggering). However, it is also necessary to consider the syndromic grouping of signs which is of greater value than a simple analysis of benignity or malignancy factors.

摘要

作者研究了119例部分性癫痫病例,这些病例选自1966年至1970年在圣保罗中心接受治疗的患者,依据以下标准:癫痫发作始于12岁之前;至少已知5年的电临床演变情况(平均病程:13年3个月)。根据癫痫的严重程度,这些病例被分为4组:(1)完全康复并停止治疗;(2)治疗期间无发作;(3)治疗期间仍有发作;(4)治疗期间频繁且严重发作。严重癫痫的特征为发作起始早(3岁之前)、存在脑病相关症状、无家族病史、多种发作类型并存,或存在特定的关键症状学表现(复杂部分性运动发作,或简单运动发作与复杂症状学的连续发作、突然跌倒或反射触发)。然而,还必须考虑体征的综合征分组,这比单纯分析良性或恶性因素更有价值。

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