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成人癫痫的纵向研究(作者译)

[Longitudinal study of epilepsies occurring in adults (author's transl)].

作者信息

Farnarier G, Iemolo F

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):531-6. doi: 10.1016/s0370-4475(81)80097-4.

Abstract

In 24% of epileptic patients the first seizure occurred between 19 and 64 years. A longitudinal study was undertaken on data from 152 subjects, ranged according to the international classification. For each group the following parameters were considered: age at onset of the first seizure; familial and individual antecedents; existence and modification in time of epileptogenic factors and of clinical and electrical interictal semiology. It was noted in particular that the occurrence of illness decreased as subjects grew older; that partial epilepsies (about 2/3 of the cases) were more common than generalized ones; that individual antecedents indicating a lesional aetiology were very frequent; that primary generalized epilepsies had a relatively favourable course, contrary to the partial epilepsies (and particularly those with complex semiological seizures). The results are discussed with reference to statistical data in the literature.

摘要

在24%的癫痫患者中,首次发作发生在19岁至64岁之间。根据国际分类对152名受试者的数据进行了纵向研究。对于每组,考虑了以下参数:首次发作的年龄;家族和个人病史;致痫因素以及临床和发作间期电信号症状学在时间上的存在和变化。特别值得注意的是,随着受试者年龄的增长,疾病的发生率降低;部分性癫痫(约占病例的2/3)比全身性癫痫更常见;表明病变病因的个人病史非常常见;原发性全身性癫痫的病程相对较好,这与部分性癫痫(尤其是那些具有复杂症状学发作的癫痫)相反。参考文献中的统计数据对结果进行了讨论。

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