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40至65岁之间发生的癫痫发作的频率及症状演变(作者译)

[Frequency and semeiological evolution of epileptic seizures occurring between 40 and 65 years of age (author's transl)].

作者信息

Vespignani H, Legras B, Weber M, Micheletti G, Micheletti M, Remy C, Rohmer F, Kurtz D, Feuerstein J

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1981 Dec;11(3-4):524-30. doi: 10.1016/s0370-4475(81)80096-2.

Abstract

458 patients who had their first epileptic fit between the ages of 40 and 65 are classified into 5 groups according to the seizure symptomatology: when the symptomatology remains unchanged, the frequency of fits is less than 1 per month in 84% of generalized fits and more than 1 per month in 52% of focal fits. When the symptomatology changes, the frequency of fits is less than 1 per month when the inaugural fit is generalized (23 out of 27) and more than 1 per month when the inaugural fit is focal (15 out of 21). Modifications of the symptomatology correlate positively with a prevalence of tumor aetiology. Primary generalized epilepsies are rare (4.4%). Non-specific secondary generalized epilepsies (including vascular, metabolic or toxic encephalopathies) account for 24.4% of the cases. Focal epilepsies are the most common form (40.7%), elementary fits being four times more frequent than complex fits.

摘要

458名年龄在40至65岁之间首次发生癫痫发作的患者,根据发作症状学被分为5组:当症状学保持不变时,在全身性发作中,84%的患者发作频率低于每月1次,在局灶性发作中,52%的患者发作频率高于每月1次。当症状学发生变化时,首发发作为全身性发作时,发作频率低于每月1次(27例中有23例),首发发作为局灶性发作时,发作频率高于每月1次(21例中有15例)。症状学的改变与肿瘤病因的患病率呈正相关。原发性全身性癫痫很少见(4.4%)。非特异性继发性全身性癫痫(包括血管性、代谢性或中毒性脑病)占病例的24.4%。局灶性癫痫是最常见的形式(40.7%),单纯性发作的频率是复杂性发作的四倍。

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