• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Human mitochondrial glycerol phosphate dehydrogenase (GPDm) isozymes.

作者信息

Shaw M A, Edwards Y H, Hopkinson D A

出版信息

Ann Hum Genet. 1982 Jan 1;46(1):11-23. doi: 10.1111/j.1469-1809.1982.tb00690.x.

DOI:10.1111/j.1469-1809.1982.tb00690.x
PMID:6808887
Abstract
  1. A hydrophobic/phospholipid electrophoretic system has been devised which makes possible the analysis of human mitochondrial glycerol phosphate dehydrogenase (E.C. 1.1.99.5. GPDM). 2. GPDM has a wide tissue distribution in both adult and foetal life and is active in cultured lymphoblastoid cells and fibroblasts but is absent from red cells. 3. The solubilization procedure does not significantly alter the kinetic properties of the enzyme (Km alpha-glycerophosphate = 0.04-0.07 M, Km PMS = 0.19-0.35 mM) but the soluble form is less thermostable. 4. Comparisons of physicochemical characteristics, tissue distribution and coenzyme requirement point to a separate genetic determination and low level of evolutionary relatedness between GPDM and its cytosolic counterpart GPDS.
摘要

相似文献

1
Human mitochondrial glycerol phosphate dehydrogenase (GPDm) isozymes.
Ann Hum Genet. 1982 Jan 1;46(1):11-23. doi: 10.1111/j.1469-1809.1982.tb00690.x.
2
The expression of human glycerol-3-phosphate dehydrogenase in human/rodent somatic-cell hybrids.人甘油-3-磷酸脱氢酶在人/啮齿动物体细胞杂种中的表达
Biochem Genet. 1985 Jun;23(5-6):405-22. doi: 10.1007/BF00499083.
3
[Functional interrelations between isozymes of dehydrogenases in the intact and denervated rabbit muscles].[完整及去神经支配兔肌肉中脱氢酶同工酶之间的功能相互关系]
Biokhimiia. 1977 Feb;42(2):311-9.
4
Solubilization and immunochemical identification of mitochondrial glycerol-3-phosphate dehydrogenase.线粒体甘油-3-磷酸脱氢酶的增溶及免疫化学鉴定
Physiol Bohemoslov. 1985;34(1):63-8.
5
Neuronal uptake and metabolism of glycerol and the neuronal expression of mitochondrial glycerol-3-phosphate dehydrogenase.神经元对甘油的摄取与代谢以及线粒体甘油-3-磷酸脱氢酶的神经元表达。
J Neurochem. 2003 May;85(4):831-42. doi: 10.1046/j.1471-4159.2003.01762.x.
6
Purification and properties of the major isozymic form of cytoplasmic glycerol-3-phosphate dehydrogenase from rabbit liver.兔肝细胞质3-磷酸甘油脱氢酶主要同工酶形式的纯化及性质
Biochim Biophys Acta. 1978 Nov 10;527(1):204-11. doi: 10.1016/0005-2744(78)90269-3.
7
Steady-state kinetics of reduction of coenzyme Q analogs by glycerol-3-phosphate dehydrogenase in brown adipose tissue mitochondria.棕色脂肪组织线粒体中甘油-3-磷酸脱氢酶还原辅酶Q类似物的稳态动力学
Arch Biochem Biophys. 1997 Aug 1;344(1):235-41. doi: 10.1006/abbi.1997.0150.
8
Dual role of free fatty acids in regulation of mitochondrial L-glycerol-3-phosphate dehydrogenase.游离脂肪酸在调节线粒体L-3-磷酸甘油脱氢酶中的双重作用。
Biochem Mol Biol Int. 1993 May;30(1):139-48.
9
Ca2+ and Mg2+ as modulators of mitochondrial L-glycerol-3-phosphate dehydrogenase.
Eur J Biochem. 1988 Jan 4;170(3):631-6. doi: 10.1111/j.1432-1033.1988.tb13744.x.
10
A comparison of the soluble and mitochondrial forms of human isocitrate dehydrogenase and an examination of the secondary isozymes derived from the soluble form.
Ann Hum Genet. 1974 May;37(4):455-67. doi: 10.1111/j.1469-1809.1974.tb01850.x.

引用本文的文献

1
The expression of human glycerol-3-phosphate dehydrogenase in human/rodent somatic-cell hybrids.人甘油-3-磷酸脱氢酶在人/啮齿动物体细胞杂种中的表达
Biochem Genet. 1985 Jun;23(5-6):405-22. doi: 10.1007/BF00499083.
2
Mitochondrial alpha-glycerol phosphate dehydrogenase activity in IIA fibres of the rat lateral gastrocnemius muscle; the effect of Ca2+ and ATP.
Histochem J. 1990 Feb;22(2):119-24. doi: 10.1007/BF01885791.