Jarrett R J, Shipley M J, Rose G
Br Med J (Clin Res Ed). 1982 Aug 21;285(6341):535-7. doi: 10.1136/bmj.285.6341.535.
Ten-year mortality rates in men aged 40-64 years in the Whitehall Study were analysed in relation to weight and height at the initial examination. At ages 40-49 "all-causes" mortality increased with increasing body mass index; but this simple relation disappeared at older ages, where there was an increased mortality in the lowest quintile of body mass index. The "all-ages" relation was "J"-shaped, and this could not be explained by the confounding effects of blood pressure, cholesterol values, and cigarette smoking. Some, but not all, of the J shape was due to a high short-term mortality in thin men from cancers (presumably already present at examination). At younger ages mortality from coronary heart disease was positively related to body mass index, but this depended on its association with other risk factors. Mortality from causes other than cancers or coronary heart disease was highest in the lowest quintile of body mass index.
白厅研究对40 - 64岁男性的十年死亡率与初次检查时的体重和身高进行了分析。在40 - 49岁时，“全因”死亡率随体重指数增加而上升；但在老年时，这种简单关系消失了，体重指数最低的五分之一人群死亡率增加。“所有年龄段”的关系呈“J”形，这无法用血压、胆固醇值和吸烟的混杂效应来解释。“J”形的部分（而非全部）原因是瘦人因癌症导致的短期高死亡率（可能在检查时就已存在）。在较年轻年龄段，冠心病死亡率与体重指数呈正相关，但这取决于其与其他风险因素的关联。体重指数最低的五分之一人群中，癌症或冠心病以外原因导致的死亡率最高。
