食蚊鱼克隆遗传基因组的遗传剖析：II. 沉默羧酸酯酶等位基因的研究。
Genetic dissection of clonally inherited genomes of Poeciliopsis: II. Investigation of a silent carboxylesterase allele.
作者信息
Spinella D G, Vrijenhoek R C
出版信息
Genetics. 1982 Feb;100(2):279-86. doi: 10.1093/genetics/100.2.279.
Abstract
According to the ratchet mechanism hypothesis, deleterious mutations should accumulate in clonal genomes of unisexual fish of the genus Poeciliopsis. This study defines one such mutant, a silent carboxylesterase allele (ES-5 degrees) which is found in the heterozygous condition in a particular population of P. monacha-occidentalis. An antiserum to purified Poeciliopsis carboxylesterase cross-reacts with the gene product of the Es-5 degrees allele upon immunoelectrophoresis. This finding of cross-reacting material associated with the Es-5 degrees allele provides a useful marker for the breeding of a carboxylesterase deficient strain.
摘要
根据棘轮机制假说，有害突变应在食蚊鱼属单性鱼类的克隆基因组中积累。本研究定义了这样一个突变体，即一个沉默的羧酸酯酶等位基因（ES-5°），它在西方食蚊鱼的一个特定种群中以杂合状态被发现。针对纯化的食蚊鱼羧酸酯酶的抗血清在免疫电泳时与Es-5°等位基因的基因产物发生交叉反应。这一与Es-5°等位基因相关的交叉反应物质的发现为培育羧酸酯酶缺陷菌株提供了一个有用的标记。
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本文引用的文献
1
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2
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Mutat Res. 1964 May;106:2-9. doi: 10.1016/0027-5107(64)90047-8.
3
Linkage conservation of homologous esterase loci in fish (Cyprinodontoidei: Poeciliidae).鱼类（鲤齿亚目：花鳉科）同源酯酶基因座的连锁保守性
Biochem Genet. 1980 Feb;18(1-2):103-15. doi: 10.1007/BF00504363.
4
Linkage analysis of seventeen loci in poeciliid fish (genus Poeciliopsis).
J Hered. 1982 Jan-Feb;73(1):19-23. doi: 10.1093/oxfordjournals.jhered.a109568.
5
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Can J Zool. 1968 Sep;46(5):1013-7. doi: 10.1139/z68-141.
6
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Scand J Immunol Suppl. 1973;1:47-56. doi: 10.1111/j.1365-3083.1973.tb03778.x.
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J Hered. 1977 Sep-Oct;68(5):301-6. doi: 10.1093/oxfordjournals.jhered.a108841.
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