实验大鼠（褐家鼠）中酯酶-18（ES-18）的遗传变异和生化特性：V连锁群中酯酶簇2的一个新基因座
Genetic variation and biochemical properties of esterase-18 (ES-18) in the laboratory rat (Rattus norvegicus): a new locus of esterase cluster 2 in linkage group V.
作者信息
Kluge R, Hedrich H J, von Deimling O
机构信息
Abteilung für Versuchstierkunde, Medizinischen Fakultät der RWTH Aachen, Bundersrepublik Deutschland.
出版信息
Biochem Genet. 1990 Feb;28(1-2):57-68. doi: 10.1007/BF00554821.
A new liver-specific rat carboxylesterase isozyme (EC 3.1.1.1) designated esterase-18 (ES-18) is described. Genetic variation of ES-18 was examined in 93 inbred strains and substrains and a structural locus Es-18 was suggested, coding for either the presence (Es-18a) or the absence (Es-18b) of the isozyme. Linkage studies involving two backcross series revealed that Es-18 resides in cluster 2 of LGV. No recombination between Es-18 and other cluster 2 loci was found in 19 lines of two RI strain sets or in the backcross series.
本文描述了一种新的大鼠肝脏特异性羧酸酯酶同工酶（EC 3.1.1.1），命名为酯酶-18（ES-18）。在93个近交系和亚系中检测了ES-18的遗传变异，并提出了一个结构基因座Es-18，它编码该同工酶的存在（Es-18a）或缺失（Es-18b）。涉及两个回交系列的连锁研究表明，Es-18位于大鼠连锁群Ⅱ的第2簇。在两个重组近交系（RI）品系组的19个品系或回交系列中，未发现Es-18与其他第2簇基因座之间发生重组。
Zotero 插件