MacDonald T T, Bashore M, Carter P B
Infect Immun. 1982 Jul;37(1):390-2. doi: 10.1128/iai.37.1.390-392.1982.
Intraperitoneal or intraduodenal pretreatment of mice with dead Corynebacterium parvum failed to produce significant nonspecific resistance to Salmonella enteritidis infection in the Peyer's patches of the small intestine. However, mice pretreated with a single oral infection of live Listeria monocytogenes were capable of restricting the growth of S. enteritidis in the Peyer's patches. The ability of L. monocytogenes to induce nonspecific resistance was associated with the ability of this organism to cause an increase in the number of macrophages in the Peyer's patches.
用死短小棒状杆菌对小鼠进行腹腔内或十二指肠内预处理，未能在小肠派尔集合淋巴结中产生对肠炎沙门氏菌感染的显著非特异性抵抗力。然而，用活单核细胞增生李斯特菌单次口服感染预处理的小鼠能够限制肠炎沙门氏菌在派尔集合淋巴结中的生长。单核细胞增生李斯特菌诱导非特异性抵抗力的能力与其导致派尔集合淋巴结中巨噬细胞数量增加的能力相关。
