Adell R, Lekholm U, Rockler B, Brånemark P I
Int J Oral Surg. 1981 Dec;10(6):387-416. doi: 10.1016/s0300-9785(81)80077-4.
Osseointegration implies a firm, direct and lasting connection between vital bone and screw-shaped titanium implants of defined finish and geometry-fixtures. Thus, there is no interposed tissue between fixture and bone. Osseointegration can only be achieved and maintained by a gentle surgical installation technique, a long healing time and a proper stress distribution when in function. During a 15-year period (1965-1980), 2768 fixtures were installed in 410 edentulous jaws of 371 consecutive patients. All patients were provided with facultatively removable bridges and were examined at continuous yearly controls. The surgical and prosthetic technique was developed and evaluated over a pilot period of 5 years. The results of standardized procedures applied on a consecutive clinical material with an observation time of 5-9 years were thought to properly reflect the potential of the method. In this group, 130 jaws were provided with 895 fixtures, and of these 81% of the maxillary and 91% of the mandibular fixtures remained stable, supporting bridges. In 89% of the maxillary and 100% of the mandibular cases, the bridges were continuously stable. During healing and the first year after connection of the bridge, the mean value for marginal bone loss was 1.5 mm. Thereafter only 0.1 mm was lost annually. The clinical results achieved with bridges on osseointegrated fixtures fulfill and exceed the demands set by the 1978 Harvard Conference on successful dental implantation procedures.
骨结合意味着在有活力的骨组织与具有特定表面处理和几何形状的螺旋形钛种植体(种植体)之间形成牢固、直接且持久的连接。因此,在种植体与骨之间不存在插入组织。骨结合只能通过轻柔的手术植入技术、较长的愈合时间以及功能状态下适当的应力分布来实现和维持。在1965年至1980年的15年期间,为371例连续患者的410个无牙颌植入了2768颗种植体。所有患者均配备了可摘义齿,并每年进行连续检查。手术和修复技术在5年的试验期内得到了发展和评估。对连续临床资料应用标准化程序并观察5至9年的结果被认为能恰当反映该方法的潜力。在这组患者中,130个颌骨植入了895颗种植体,其中上颌种植体的81%和下颌种植体的91%保持稳定,支撑着义齿。在89%的上颌病例和100%的下颌病例中,义齿持续稳定。在愈合期以及义齿连接后的第一年,边缘骨吸收的平均值为1.5毫米。此后每年仅吸收0.1毫米。骨结合种植体上的义齿所取得的临床结果达到并超过了1978年哈佛成功牙种植手术会议设定的要求。