Palabost-Charles L
Biochem Genet. 1982 Jun;20(5-6):461-74. doi: 10.1007/BF00484697.
Three sets of experiments have been conducted in order to evaluate the role of natural selection at the alpha-Gpdh locus in Drosophila melanogaster. (1) The evolution of the F-allele frequency has been followed for many generations in 13 experimental populations having different genetic backgrounds. (2) Egg-to-adult viability has been measured in synthetic populations derived from one locality (Brouilly) and the results have been compared with those of a previous experiment involving a different local population (Tostes). (3) The effects of sodium octanoate on egg-to-adult viability have been measured on the genotypes FF, FS, SF, and SS. The results demonstrate that selection operates on a small block of genes which includes the alpha-Gpdh locus.
为了评估自然选择在黑腹果蝇α - Gpdh基因座上的作用，已进行了三组实验。（1）在13个具有不同遗传背景的实验种群中，对F等位基因频率的演变进行了多代跟踪。（2）在来自一个地点（布鲁伊）的合成种群中测量了卵到成虫的存活率，并将结果与之前涉及不同当地种群（托斯特）的实验结果进行了比较。（3）在基因型FF、FS、SF和SS上测量了辛酸钠对卵到成虫存活率的影响。结果表明，选择作用于一个包含α - Gpdh基因座的小基因块。
