Dawood M Y, Jarrett J C, Choe J K
Fertil Steril. 1982 Oct;38(4):415-8. doi: 10.1016/s0015-0282(16)46573-8.
The case of a patient who developed partial hypopituitarism (hypogonadotropism and growth hormone deficiency) following transphenoidal removal of a prolactinoma is described. Hypogonadotropism persisted despite restoration of normoprolactinemia with bromocriptine therapy. Successful induction of ovulation with human menopausal gonadotropin (hMG) and bromocriptine suppression of the hyperprolactinemia was carried out, resulting in a pregnancy. The pros and cons of operative and nonoperative management of hyperprolactinemia are discussed.
本文描述了一例患者,该患者在经蝶窦切除催乳素瘤后出现部分垂体功能减退(性腺功能减退和生长激素缺乏)。尽管使用溴隐亭治疗使催乳素血症恢复正常,但性腺功能减退仍持续存在。使用人绝经期促性腺激素(hMG)成功诱导排卵,并使用溴隐亭抑制高催乳素血症,最终导致怀孕。文中还讨论了高催乳素血症手术治疗和非手术治疗的利弊。