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华氏巨球蛋白血症、多发性骨髓瘤及风湿性疾病中的血清淀粉样蛋白P成分(Protein SAP)

Protein SAP (serum amyloid P-component) in Waldenström's macroglobulinaemia, multiple myeloma and rheumatic diseases.

作者信息

Strachan A F, Johnson P M

出版信息

J Clin Lab Immunol. 1982 Sep;8(3):153-6.

PMID:6813503
Abstract

Serum amyloid P-component (protein SAP) levels in patients with Waldenström's macroglobulinaemia have been determined to be markedly elevated (83 +/- 34 micrograms/ml) compared with healthy adult controls (35 +/- 11 micrograms/ml) and patients with multiple myeloma (39 +/- 17 micrograms/ml). Seropositive rheumatoid arthritis and ankylosing spondylitis patients demonstrated slightly elevated protein SAP levels compared with normals and systemic lupus erythematosus patients, but these values were indistinguishable from those for patients with amyloidosis associated with a rheumatic disease.

摘要

已确定华氏巨球蛋白血症患者的血清淀粉样蛋白P成分(蛋白SAP)水平与健康成人对照组(35±11微克/毫升)和多发性骨髓瘤患者(39±17微克/毫升)相比显著升高(83±34微克/毫升)。血清阳性类风湿性关节炎和强直性脊柱炎患者的蛋白SAP水平与正常人和系统性红斑狼疮患者相比略有升高,但这些值与患有与风湿性疾病相关淀粉样变性的患者的值无明显差异。

相似文献

1
Protein SAP (serum amyloid P-component) in Waldenström's macroglobulinaemia, multiple myeloma and rheumatic diseases.华氏巨球蛋白血症、多发性骨髓瘤及风湿性疾病中的血清淀粉样蛋白P成分(Protein SAP)
J Clin Lab Immunol. 1982 Sep;8(3):153-6.
2
Serum amyloid P component levels are not decreased in patients with systemic lupus erythematosus and do not rise during an acute phase reaction.系统性红斑狼疮患者的血清淀粉样蛋白P成分水平并未降低,且在急性期反应期间也不会升高。
Ann Rheum Dis. 2004 Jul;63(7):831-5. doi: 10.1136/ard.2002.004796.
3
[Determination of blood viscosity in rheumatic diseases].[风湿性疾病中血液粘度的测定]
Nouv Presse Med. 1977 Sep 17;6(30):2686.
4
[Immunoglobulin levels in the serum of patients with myeloma and Waldenström's macroglobulinemia].[骨髓瘤和华氏巨球蛋白血症患者血清中的免疫球蛋白水平]
C R Seances Soc Biol Fil. 1971;165(5):1191-4.
5
[Serum protein immunofixation in malignant hemopathies other than multiple myeloma and Waldenstrom's macroglobulinemia].[除多发性骨髓瘤和华氏巨球蛋白血症外的恶性血液病中的血清蛋白免疫固定电泳]
Ann Biol Clin (Paris). 2002 Sep-Oct;60(5):565-70.
6
[Amyloidosis. II. Current pathogenetic and clinico-nosographic aspects].[淀粉样变性。II. 当前的发病机制及临床分类学方面]
Minerva Med. 1980 Jun 23;71(25):1801-13.
7
[Acute phase proteins in monoclonal gammapathies].[单克隆丙种球蛋白病中的急性期蛋白]
Pathol Biol (Paris). 1991 Oct;39(8):769-73.
8
[Inflammatory rheumatism and Waldenström's macroglobulinemia].
Rev Rhum Mal Osteoartic. 1974 Oct;41(10):573-7.
9
Serum and urine light chain levels in benign monoclonal gammapathies, multiple myeloma and Waldenström's macroglobulinaemia.良性单克隆丙种球蛋白病、多发性骨髓瘤和华氏巨球蛋白血症中的血清和尿轻链水平。
Clin Exp Immunol. 1968 Nov;3(9):911-21.
10
Polyacrylamide electrophoresis. II. Study of serum proteins in multiple myeloma and Waldenstrom's macroglobulinemia.
Riv Ist Sieroter Ital. 1967 Jan-Feb;42(1):17-23.

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Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation.关键进展:Th-1细胞因子抑制,而Th-2细胞因子促进纤维细胞分化。
J Leukoc Biol. 2008 Jun;83(6):1323-33. doi: 10.1189/jlb.1107782. Epub 2008 Mar 10.
5
Serum amyloid P component levels are not decreased in patients with systemic lupus erythematosus and do not rise during an acute phase reaction.系统性红斑狼疮患者的血清淀粉样蛋白P成分水平并未降低,且在急性期反应期间也不会升高。
Ann Rheum Dis. 2004 Jul;63(7):831-5. doi: 10.1136/ard.2002.004796.
6
Inhibition of fibrocyte differentiation by serum amyloid P.血清淀粉样蛋白P对纤维细胞分化的抑制作用。
J Immunol. 2003 Nov 15;171(10):5537-46. doi: 10.4049/jimmunol.171.10.5537.
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Antibody to streptococcal cell wall peptidoglycan-polysaccharide polymers in seropositive and seronegative rheumatic disease.血清阳性和血清阴性风湿性疾病中抗链球菌细胞壁肽聚糖-多糖聚合物的抗体
Clin Exp Immunol. 1984 Jan;55(1):115-24.