Courcol R J, Roussel-Delvallez M, Puech F, Delecour M, Martin G R
Biol Neonate. 1982;42(3-4):166-73. doi: 10.1159/000241591.
Quantitative bacteriological analysis of amniotic fluid (AF) was performed on 60 fluid samples collected by catheter from 50 selected labor patients regarded as liable to infection. AF cultures were positive in 52 cases. The bacterial colony counts ranged from less than 10(2) colony-forming units (CFU) per milliliter to 10(9) CFU/ml. Pathogenic bacteria in neonates such as group B Streptococcus, Escherichia coli, and Listeria monocytogenes were encountered with numerations equal to or greater than 10(7) CFU/ml in groups with clinical findings. An excellent correlation was noted between bacterial counts in AF and clinical data (p less than 0.00006). The results confirm that the quantitative bacteria analysis of the AF is a useful tool for evaluation of an infection risk for neonates.
对50例被认为易感染的待产患者，通过导管采集了60份羊水样本进行羊水定量细菌学分析。羊水培养52例呈阳性。细菌菌落计数范围从每毫升少于10²菌落形成单位（CFU）到10⁹CFU/ml。在有临床症状的组中，新生儿的致病菌如B族链球菌、大肠杆菌和单核细胞增生李斯特菌，其计数等于或大于10⁷CFU/ml。羊水细菌计数与临床数据之间存在极佳的相关性（p<0.00006）。结果证实，羊水定量细菌分析是评估新生儿感染风险的有用工具。
