Bobitt J R, Ledger W J
Obstet Gynecol. 1978 Jan;51(1):56-62.
Indirect evidence suggests that amnionitis, in the absence of maternal symptoms, contributes to neonatal morbidity. The incidence is unknown because diagnostic techniques are not available. A quantitative amniotic fluid analysis of bacteria, white blood cells, and lactic dehydrogenase levels was performed during labor among 28 patients considered to be a risk for infection. Thirteen of 16 patients with bacterial colony counts greater than 10(3)/ml subsequently developed maternal infection had a premature delivery, neonatal sepsis, or a combination of these factors. Maternal fever was a late sign in clinical infection and was frequently absent in cases of premature delivery associated with microbiologic evidence of amnionitis. Amniotic fluid analysis may be of value in diagnosing unrecognized amnionitis among patients delivering prematurely and those requiring nonelective cesarean section.
间接证据表明，在没有母体症状的情况下，羊膜炎会导致新生儿发病。由于缺乏诊断技术，其发病率尚不清楚。对28例被认为有感染风险的患者在分娩期间进行了羊水细菌、白细胞和乳酸脱氢酶水平的定量分析。16例细菌菌落计数大于10(3)/ml的患者中，有13例随后出现母体感染、早产、新生儿败血症或这些因素的组合。母体发热是临床感染的晚期体征，在与羊膜炎微生物学证据相关的早产病例中常常不存在。羊水分析对于诊断早产患者和需要非选择性剖宫产的患者中未被识别的羊膜炎可能有价值。
