Gibbs R S, Blanco J D, St Clair P J, Castaneda Y S
J Infect Dis. 1982 Jan;145(1):1-8. doi: 10.1093/infdis/145.1.1.
Amniotic fluid was collected through an intrauterine catheter from 52 women with clinical intraamniotic infection and from 52 uninfected matched control women. The amniotic fluid was cultured quantitatively for anaerobes and aerobes. Patients with intraamniotic infection were matched with the control women on the basis of gestational age, interval from membrane rupture to specimen collection, and interval from membrane rupture to delivery. The patients with intraamniotic infection had a significantly higher mean temperature (38.4 vs. 37.1 C) and a higher mean leukocyte count (15,740 vs. 11,740 cells/mm3). In 80.6% of specimens from the women with intraamniotic infection and 30.8% of those from the control subjects, greater than or equal to 10(2) colony-forming units (cfu)/ml were isolated from the amniotic fluid (P less than 0.001). Also, in 69.2% of the former and 7.7% of the latter, there were greater than or equal to 10(2) cfu of isolates considered to be "high-virulence" isolates/ml (P less than 0.001).
通过宫内导管从52例临床诊断为羊膜腔内感染的女性以及52例与之匹配的未感染对照女性中采集羊水。对羊水进行需氧菌和厌氧菌的定量培养。羊膜腔内感染患者与对照女性在孕周、胎膜破裂至标本采集的间隔时间以及胎膜破裂至分娩的间隔时间方面进行匹配。羊膜腔内感染患者的平均体温显著更高（38.4对37.1℃），平均白细胞计数也更高（15,740对11,740个细胞/mm³）。在羊膜腔内感染女性的80.6%的标本以及对照受试者的30.8%的标本中，从羊水中分离出的菌落形成单位（cfu）大于或等于10²/ml（P<0.001）。此外，在前者的69.2%以及后者的7.7%中，每毫升分离出的被认为是“高毒力”菌株的cfu大于或等于10²（P<0.001）。
