Nolan L S, Shoemaker W C
Crit Care Med. 1982 Nov;10(11):762-4. doi: 10.1097/00003246-198211000-00013.
The usefulness of noninvasive transcutaneous oxygen (PtcO2) and carbon dioxide (PtcCO2) sensors as well as invasive monitoring of flow and oxygen transport were evaluated in the perioperative period of a small series of high risk surgical patients. We used the pattern of physiological events preceding intraoperative death as the criteria for evaluation of the relative usefulness of these variables. Cardiac output (CO), oxygen delivery (DO2), and O2 consumption (VO2) provided the earliest warning of impending circulatory deterioration and were most useful during critical nonlethal circulatory episodes; these were closely paralleled by the PtcO2 index (PtcO2/PaO2); the PtcCO2 was less sensitive. Heart rate (HR) and mean arterial pressure (MAP) were highly variable with frequent changes unrelated to change in flow and O2 transport.
在一小部分高风险手术患者的围手术期，对非侵入性经皮氧分压（PtcO2）和二氧化碳分压（PtcCO2）传感器以及血流和氧输送的侵入性监测的有用性进行了评估。我们将术中死亡前的生理事件模式作为评估这些变量相对有用性的标准。心输出量（CO）、氧输送（DO2）和氧消耗（VO2）提供了即将发生循环恶化的最早预警，并且在关键的非致命循环事件中最有用；这些与PtcO2指数（PtcO2/PaO2）密切平行；PtcCO2的敏感性较低。心率（HR）和平均动脉压（MAP）变化很大，频繁变化且与血流和氧输送的变化无关。
