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Biologic effect of a hybrid preparation of human chorionic gonadotropin in human subjects.

作者信息

Rosemberg E

出版信息

Reproduccion. 1982 Apr-Jun;6(2):117-32.

PMID:6814969
Abstract

Alpha and beta-hCG subunits were recombined generating a hybrid hCG preparation (AB1ER-CR-2XY) which met the required specifications of a pharmaceutical product. The biologic activity contained in each vial of AB1ER-CR-2XY was equivalent to 10 000IU of hCG-IS. This preparation was given as a single dose of 10 000IU by the i.m. route to four female subjects presenting unexplained infertility. The hCG hybrid was demonstrated to effect gonadal stimulation in humans.

摘要

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