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多囊卵巢综合征患者体外成熟过程中，10000国际单位与人绒毛膜促性腺激素20000国际单位启动治疗的随机对照试验

Randomized, controlled trial of priming with 10,000 IU versus 20,000 IU of human chorionic gonadotropin in women with polycystic ovary syndrome who are undergoing in vitro maturation.

作者信息

Gulekli Bulent, Buckett William M, Chian Ri-Cheng, Child Timothy J, Abdul-Jalil A Kamal, Tan Seang Lin

机构信息

McGill Reproductive Centre, Royal Victoria Hospital, Montreal, Québec, Canada.

出版信息

Fertil Steril. 2004 Nov;82(5):1458-9. doi: 10.1016/j.fertnstert.2004.04.043.

DOI:10.1016/j.fertnstert.2004.04.043
PMID:15533381
Abstract

Preretrieval priming with 10,000 IU hCG can improve oocyte maturation rates in vitro for women undergoing in vivo maturation treatment, though the optimum dose is unknown. This prospective, randomized, controlled trial demonstrated no improvement in oocyte maturation rates with 20,000 IU of hCG compared with 10,000 IU of hCG and therefore no benefit of the higher dose.

摘要

对于接受体内成熟治疗的女性，使用10,000国际单位人绒毛膜促性腺激素（hCG）进行检索前预处理可提高体外卵母细胞成熟率，尽管最佳剂量尚不清楚。这项前瞻性、随机、对照试验表明，与10,000国际单位hCG相比，20,000国际单位hCG并未提高卵母细胞成熟率，因此高剂量并无益处。

相似文献

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Randomized, controlled trial of priming with 10,000 IU versus 20,000 IU of human chorionic gonadotropin in women with polycystic ovary syndrome who are undergoing in vitro maturation.多囊卵巢综合征患者体外成熟过程中，10000国际单位与人绒毛膜促性腺激素20000国际单位启动治疗的随机对照试验
Fertil Steril. 2004 Nov;82(5):1458-9. doi: 10.1016/j.fertnstert.2004.04.043.
2
Exposure to human chorionic gonadotropin during in vitro maturation does not improve the maturation rate and developmental potential of immature oocytes from patients with polycystic ovary syndrome.在体外成熟过程中暴露于人类绒毛膜促性腺激素并不能提高多囊卵巢综合征患者未成熟卵母细胞的成熟率和发育潜能。
Fertil Steril. 2008 Jan;89(1):98-103. doi: 10.1016/j.fertnstert.2007.02.021. Epub 2007 May 24.
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[In vitro maturation and fertilization of oocytes from unstimulated cycles in women with infertility due to polycystic ovary syndrome].[多囊卵巢综合征所致不孕症女性未刺激周期卵母细胞的体外成熟与受精]
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Triggering final oocyte maturation using different doses of human chorionic gonadotropin: a randomized pilot study in patients with polycystic ovary syndrome treated with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating hormone.使用不同剂量人绒毛膜促性腺激素触发最终卵母细胞成熟：一项在接受促性腺激素释放激素拮抗剂和重组促卵泡激素治疗的多囊卵巢综合征患者中的随机试点研究
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Natural-cycle in vitro fertilization combined with in vitro maturation of immature oocytes is a potential approach in infertility treatment.自然周期体外受精联合未成熟卵母细胞体外成熟是不孕症治疗的一种潜在方法。
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Impact of insulin resistance on the developmental potential of immature oocytes retrieved from human chorionic gonadotropin-primed women with polycystic ovary syndrome undergoing in vitro maturation.
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Prolonged HCG action affects angiogenic substances and improves follicular maturation, oocyte quality and fertilization competence in patients with polycystic ovarian syndrome.延长人绒毛膜促性腺激素（HCG）作用时间可影响血管生成物质，并改善多囊卵巢综合征患者的卵泡成熟、卵母细胞质量和受精能力。
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Priming with human chorionic gonadotropin before retrieval of immature oocytes in women with infertility due to the polycystic ovary syndrome.
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Oocytes collected 60 hours after human chorionic gonadotropin administration from patients with polycystic ovary syndrome who underwent limited ovarian stimulation resulted in clinical pregnancies and the delivery of a healthy baby.对接受有限卵巢刺激的多囊卵巢综合征患者，在注射人绒毛膜促性腺激素60小时后采集的卵母细胞，实现了临床妊娠并分娩出一名健康婴儿。
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In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction.多囊卵巢综合征不孕妇女在接受辅助生殖时的体外成熟。
Cochrane Database Syst Rev. 2018 Nov 15;11(11):CD006606. doi: 10.1002/14651858.CD006606.pub4.
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Human chorionic gonadotrophin priming for fertility treatment with in vitro maturation.
用于体外成熟生育治疗的人绒毛膜促性腺激素预处理
Cochrane Database Syst Rev. 2016 Nov 16;11(11):CD008720. doi: 10.1002/14651858.CD008720.pub2.
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IVM is an alternative for patients with PCO after failed conventional IVF attempt.IVM 是常规体外受精（IVF）失败后 PCO 患者的一种替代选择。
J Assist Reprod Genet. 2011 Jun;28(6):495-9. doi: 10.1007/s10815-011-9591-z. Epub 2011 Jun 7.
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Controversies in IVM.体外受精的争议。
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Comparison of fertilization and embryonic development in sibling in vivo matured oocytes retrieved from different sizes follicles from in vitro maturation cycles.比较体外成熟周期中从不同大小卵泡中获取的同胞体内成熟卵母细胞的受精和胚胎发育情况。
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