Southern L L, Baker D H
J Anim Sci. 1982 Oct;55(4):857-66. doi: 10.2527/jas1982.554857x.
Four experiments were conducted to investigate the arginine x lysine interaction in young pigs. Excess supplemental arginine (.67 to 2% of diet) decreased weight gain and feed intake, but had no effect on efficiency of feed utilization. Lysine supplementation (.5 or 2.5%) did not ameliorate the adverse effects of excess arginine. Decreasing the arginine content to .8% from a level routinely supplied by typical swine diets (1.3%) did not improve pig performance. Excess supplemental arginine increased plasma arginine and ornithine concentrations and decreased plasma lysine and histidine concentrations; several other amino acids were decreased in plasma as well. Feeding 2.8% total dietary arginine resulted in a dramatic increase in urinary excretion of arginine, ornithine, citrulline, lysine, histidine and cystine. From these results it is concluded that the adverse effects of excess arginine represent classic amino acid imbalance rather than amino acid antagonism.
进行了四项试验以研究仔猪中精氨酸与赖氨酸的相互作用。过量补充精氨酸（占日粮的0.67%至2%）会降低体重增加和采食量，但对饲料利用效率没有影响。补充赖氨酸（0.5%或2.5%）并不能改善过量精氨酸的不良影响。将精氨酸含量从典型猪日粮常规提供的水平（1.3%）降至0.8%并不能提高猪的生产性能。过量补充精氨酸会增加血浆精氨酸和鸟氨酸浓度，并降低血浆赖氨酸和组氨酸浓度；其他几种氨基酸在血浆中也有所降低。饲喂总日粮精氨酸含量为2.8%会导致精氨酸、鸟氨酸、瓜氨酸、赖氨酸、组氨酸和胱氨酸的尿排泄量显著增加。从这些结果可以得出结论，过量精氨酸的不良影响代表典型的氨基酸失衡而非氨基酸拮抗作用。
