Ventz M, Meng W, Franke G, Weber A, Hampel R
Z Gesamte Inn Med. 1982 Sep 1;37(17):564-7.
It is reported on the performance of the 400 microgram TRH/TSH test in adipose persons in the course of a zero diet and on the effects of an application of 50 micrograms tri-iodothyronine during 7 days on the TRH/TSH test on the same conditions. During total fasting the basic and TRH-stimulating TSH-level shows a slight tendency of decrease, but scarcely significant changes. After application of 50 micrograms tri-iodothyronine an unequivocal suppression of the TSH-concentration in the serum is to be recognized. By these results and with the help of literary data by means of the most sensitive test of the diagnostics of hypothyroidism a general hypofunction of the pancreas could be excluded, as it was supposed in the low T3 syndrome. But tri-iodothyronine deficiency in some tissues is still discussed at present.
本文报道了400微克促甲状腺激素释放激素(TRH)/促甲状腺激素(TSH)试验在肥胖人群零饮食期间的表现,以及在相同条件下,连续7天应用50微克三碘甲状腺原氨酸对TRH/TSH试验的影响。在完全禁食期间,基础及TRH刺激后的TSH水平呈轻微下降趋势,但变化不显著。应用50微克三碘甲状腺原氨酸后,血清中TSH浓度出现明显抑制。根据这些结果并借助文献数据,通过甲状腺功能减退症诊断中最敏感的试验,可排除此前低T3综合征中所推测的胰腺普遍功能减退。但目前仍在讨论某些组织中三碘甲状腺原氨酸缺乏的问题。