Storch W
Acta Histochem. 1982;71(1):67-72. doi: 10.1016/S0065-1281(82)80014-7.
The fluorescent patterns of autoantibodies to mitochondria, endoplasmic reticulum and ribosomes are described. Mitochondrial autoantibodies can be now divided in 10 types, microsomal antibodies at least in 3 types. Using rat renal tissue sections the typical fluorescent pattern of new antimitochondrial antibodies were: type 7, distal tubulus and third portion of proximal tubules, type 8 distal tubules, only, type 9 first and second portion of proximal tubules, type 10 strong reaction of distal and third portion of proximal tubules. The new pattern of ribosomal antibody is characterized by a cytoplasmic staining of rat hepatocytes especially in the central area of the liver lobule. The heterogeneity of cytoplasmic autoantibodies can be used as a diagnostic marker in different pathological conditions, if the different staining patterns is taken into account.
描述了针对线粒体、内质网和核糖体的自身抗体的荧光模式。线粒体自身抗体现在可分为10种类型，微粒体抗体至少有3种类型。利用大鼠肾组织切片，新型抗线粒体抗体的典型荧光模式为：7型，远端小管和近端小管的第三部分；8型，仅远端小管；9型，近端小管的第一和第二部分；10型，远端小管和近端小管的第三部分有强烈反应。核糖体抗体的新模式以大鼠肝细胞的细胞质染色为特征，特别是在肝小叶的中心区域。如果考虑到不同的染色模式，细胞质自身抗体的异质性可用作不同病理状况下的诊断标志物。
