Cassem N
J Clin Psychiatry. 1982 Nov;43(11 Pt 2):22-9.
It is not the purpose of this paper to dismiss the possibility that tricyclics may somehow cause cardiac function to deteriorate, with resulting congestive heart failure. Any patient with heart disease should receive intense clinical scrutiny for the development of cardiac symptoms--dyspnea on exertion, ankle edema, orthopnea, paroxysmal nocturnal dyspnea, rales, and the presence of an S3 are never taken lightly. These parameters should be monitored because the patient has cardiac disease, not because he or she is on a tricyclic antidepressant.
本文的目的并非排除三环类药物可能以某种方式导致心脏功能恶化并进而引发充血性心力衰竭的可能性。任何患有心脏病的患者都应接受针对心脏症状发展的严格临床检查——劳力性呼吸困难、脚踝水肿、端坐呼吸、阵发性夜间呼吸困难、啰音以及S3的出现都绝不能掉以轻心。应监测这些参数是因为患者患有心脏病,而非因为他或她正在服用三环类抗抑郁药。