Iriyama K, Mori T, Takenaka T, Teranishi T, Mori H
JPEN J Parenter Enteral Nutr. 1982 Sep-Oct;6(5):416-20. doi: 10.1177/0148607182006005416.
Changes of serum zinc level in dogs receiving either a zinc-free solution or a zinc-supplement solution during total parenteral nutrition (TPN) and the influence of variety of serum-zinc level on serum albumin and collagen-hydroxyproline (C-Hyp) in the incised intestine were investigated. The serum zinc level of zinc-free dogs that was 126.0 +/- 34.3 micrograms per deciliter at the initiation of TPN decreased significantly to 80.0 +/- 15.0 micrograms per deciliter during the one week of TPN, whereas that of zinc-supplement dogs did not decrease during the same period of TPN. Lowering of the serum albumin value was more evident in zinc-free dogs than in zinc-supplement dogs. The amount of C-Hyp in the incised area of the intestine of zinc-free dogs was 2.63 +/- 0.66 micrograms per milligram and that of zinc-supplement dogs was 4.26 +/- 1.04 micrograms per milligram and this difference was significant. It was found that serum zinc level during TPN sharply reflects a supplement of zinc, and C-Hyp in the incised gut and serum albumin of zinc-free dogs are lower than those of zinc-supplement dogs.
研究了在全肠外营养（TPN）期间接受无锌溶液或补锌溶液的犬血清锌水平的变化，以及不同血清锌水平对切开肠段血清白蛋白和胶原羟脯氨酸（C-Hyp）的影响。无锌组犬在TPN开始时血清锌水平为每分升126.0±34.3微克，在TPN的一周内显著降至每分升80.0±15.0微克，而补锌组犬在同一TPN期间血清锌水平未降低。无锌组犬血清白蛋白值的降低比补锌组犬更明显。无锌组犬切开肠段的C-Hyp含量为每毫克2.63±0.66微克，补锌组犬为每毫克4.26±1.04微克，差异显著。结果发现，TPN期间的血清锌水平能敏锐反映锌的补充情况，无锌组犬切开肠段的C-Hyp和血清白蛋白低于补锌组犬。
