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奈替米星治疗铜绿假单胞菌所致复杂性尿路感染的临床研究

[Clinical study on netilmicin in the treatment of complicated urinary tract infection caused by Pseudomonas aeruginosa].

作者信息

Murahashi I, Honda M, Maeda S, Takasaki E

出版信息

Jpn J Antibiot. 1982 Aug;35(8):1919-24.

PMID:6818388
Abstract

Netilmicin was intramuscularly injected at a daily dose of 200 mg, divided twice, for 5 to 10 days to 14 patients with complicated urinary tract infection caused by P. aeruginosa. The clinical results were excellent in 7 cases, good in 5 cases, and fair in 2 cases. Neither side effects nor abnormal values in laboratory findings were reported. The MIC of netilmicin against 14 strains of P. aeruginosa isolated from the above patients were distributed between 3.13 micrograms/ml and 12.5 micrograms/ml except 1 strain at inoculum size 10(6) cells/ml.

摘要

对14例由铜绿假单胞菌引起的复杂性尿路感染患者,每日肌内注射奈替米星,剂量为200mg,分两次注射,疗程为5至10天。临床结果为7例优,5例良,2例中。未报告有副作用或实验室检查结果异常。除1株接种量为10(6)个细胞/ml时外,奈替米星对从上述患者分离出的14株铜绿假单胞菌的最低抑菌浓度分布在3.13微克/毫升至12.5微克/毫升之间。

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