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奈替米星治疗铜绿假单胞菌所致复杂性尿路感染的临床研究

[Clinical study on netilmicin in the treatment of complicated urinary tract infection caused by Pseudomonas aeruginosa].

作者信息

Murahashi I, Honda M, Maeda S, Takasaki E

出版信息

Jpn J Antibiot. 1982 Aug;35(8):1919-24.

PMID:6818388
Abstract

Netilmicin was intramuscularly injected at a daily dose of 200 mg, divided twice, for 5 to 10 days to 14 patients with complicated urinary tract infection caused by P. aeruginosa. The clinical results were excellent in 7 cases, good in 5 cases, and fair in 2 cases. Neither side effects nor abnormal values in laboratory findings were reported. The MIC of netilmicin against 14 strains of P. aeruginosa isolated from the above patients were distributed between 3.13 micrograms/ml and 12.5 micrograms/ml except 1 strain at inoculum size 10(6) cells/ml.

摘要

对14例由铜绿假单胞菌引起的复杂性尿路感染患者,每日肌内注射奈替米星,剂量为200mg,分两次注射,疗程为5至10天。临床结果为7例优,5例良,2例中。未报告有副作用或实验室检查结果异常。除1株接种量为10(6)个细胞/ml时外,奈替米星对从上述患者分离出的14株铜绿假单胞菌的最低抑菌浓度分布在3.13微克/毫升至12.5微克/毫升之间。

相似文献

1
[Clinical study on netilmicin in the treatment of complicated urinary tract infection caused by Pseudomonas aeruginosa].奈替米星治疗铜绿假单胞菌所致复杂性尿路感染的临床研究
Jpn J Antibiot. 1982 Aug;35(8):1919-24.
2
[Clinical evaluations of netilmicin in urinary tract infections].奈替米星治疗尿路感染的临床评估
Jpn J Antibiot. 1982 Aug;35(8):1925-33.
3
[Clinical studies on netilmicin].[奈替米星的临床研究]
Jpn J Antibiot. 1984 May;37(5):802-6.
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[Clinical experience of netilmicin on chronic urinary tract infections (author's transl)].奈替米星治疗慢性尿路感染的临床经验(作者译)
Jpn J Antibiot. 1982 Jan;35(1):273-80.
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Netilmicin in the treatment of Pseudomonas bacteremia.奈替米星治疗铜绿假单胞菌菌血症。
Clin Ther. 1985;7(3):338-46.
6
Treatment of complicated urinary tract infection caused by Pseudomonas aeruginosa--a comparison of the efficacy of ceftazidime with that of netilmicin.铜绿假单胞菌所致复杂性尿路感染的治疗——头孢他啶与奈替米星疗效比较
J Antimicrob Chemother. 1981 Sep;8 Suppl B:323-4. doi: 10.1093/jac/8.suppl_b.323.
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Netilmicin therapy of serious Gram-negative bacillary infections.奈替米星治疗严重革兰氏阴性杆菌感染
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Netilmicin in urinary tract infections.
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[Clinical trials of netilmicin against respiratory tract infection].奈替米星治疗呼吸道感染的临床试验
Jpn J Antibiot. 1982 Aug;35(8):1907-10.
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Comparison of postantibiotic effects of imipenem and netilmicin alone and in combination against Pseudomonas aeruginosa.
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