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[实验性蛔虫病后猪血液中T淋巴细胞和B淋巴细胞数量的变化]

[Changes in the number of T and B lymphocytes in the blood of pigs after experimental ascaridiosis].

作者信息

Borosková Z, Benková M, Alexander R

出版信息

Vet Med (Praha). 1982 Dec;27(12):741-6.

PMID:6818751
Abstract

The changes in the number of the T and B dependent cells in the peripheral blood were studied after experimental invasion of piglets (live weight 8-10 kg) with the eggs of Ascaris suum (50 000 eggs per piglet). The detection of both cell populations by two rosette methods (E and EAC) showed that their first rise set in on the third day from invasion. The maximum occurrence of the T and B cells was recorded 17 days from invasion; on the 20th day from invasion their number returned to the initial level. At the same time, the test animals were studied as to the white component of their blood picture. The results of the haematological study were found to show a direct relationship with the results of the rosette methods. It follows from the study that in the specific host the susceptibility of the T and B lymphoid cells to the antigenic signal starts already in the early stage of invasion.

摘要

研究了用猪蛔虫卵(每头仔猪50000个卵)对体重8 - 10千克的仔猪进行实验性感染后,外周血中T细胞和B依赖细胞数量的变化。用两种花环法(E和EAC)检测这两种细胞群体,结果显示感染后第三天它们的数量开始首次增加。感染后第17天记录到T细胞和B细胞出现的最大值;感染后第20天,它们的数量恢复到初始水平。同时,对实验动物的血常规白细胞成分进行了研究。血液学研究结果与花环法结果显示出直接关系。从该研究可以得出,在特定宿主体内,T淋巴细胞和B淋巴细胞对抗原信号的敏感性在感染早期就已开始。

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