Tomolina N, Schmitt E, Sinn W, Klinkmann H
Z Urol Nephrol. 1982 Sep;75(9):669-73.
The results of a 6-month Prednisone therapy (initial 60 mg/d with later reduction of dose) are given as the immediate results of therapy (after 6 months in 128 patients) and as a late result (after 11 years in 107 patients). The course is evaluated on the basis of clinical symptoms. The early effect proved to be an improvement in 2/3 of all cases, whereby 22% were total remissions. In the late results patients with primary total remission showed the best functional results. This therapy is justified in nephrotic, proteinuric-hypertonic, purely proteinuric and proteinuric-haematuric forms of mesangioproliferative glomerulonephritis.
泼尼松治疗6个月(初始剂量为60毫克/天,随后逐渐减量)的结果作为治疗的即时结果(128例患者治疗6个月后)和远期结果(107例患者治疗11年后)给出。根据临床症状评估病程。早期效果显示,所有病例中有2/3病情改善,其中22%完全缓解。在远期结果中,原发性完全缓解的患者功能结果最佳。这种治疗方法适用于系膜增生性肾小球肾炎的肾病型、蛋白尿性高血压型、单纯蛋白尿型和蛋白尿血尿型。