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黏液病毒菌素,一类来自绿色黏球菌(黏杆菌目)的抗生素。

The myxovirescins, a family of antibiotics from Myxococcus virescens (Myxobacterales).

作者信息

Gerth K, Irschik H, Reichenbach H, Trowitzsch W

出版信息

J Antibiot (Tokyo). 1982 Nov;35(11):1454-9. doi: 10.7164/antibiotics.35.1454.

Abstract

The myxobacterium, Myxococcus virescens strain Mx v48 produced a family of at least 12 closely related antibiotics, the myxovirescins. At a concentration of 1 to 5 micrograms/ml, the main component, myxovirescin A, was bactericidal for many Gram-negative bacteria, in particular enterobacteria, and at 20 to 50 micrograms/ml it also inhibited some pseudomonads and Gram-positive bacteria. The antibiotics seem to interfere with cell wall synthesis. The molecular formula of myxovirescin A was C35H61NO8. It is a new antibiotic.

摘要

粘细菌黄绿粘球菌Mx v48菌株产生了一族至少12种密切相关的抗生素,即黄绿菌素。在浓度为1至5微克/毫升时,主要成分黄绿菌素A对许多革兰氏阴性菌具有杀菌作用,尤其是肠杆菌,而在20至50微克/毫升时,它也能抑制一些假单胞菌和革兰氏阳性菌。这些抗生素似乎会干扰细胞壁的合成。黄绿菌素A的分子式为C35H61NO8。它是一种新型抗生素。

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