Kumar S, Abcarian H, Prasad M L, Lakshmanan S
Dis Colon Rectum. 1983 Jan;26(1):22-4. doi: 10.1007/BF02554673.
In an effort to elucidate whether bacteremia occurs during endoscopic examination of the lower gastrointestinal tract, two prospective studies were undertaken involving patients undergoing colonoscopy and proctosigmoidoscopy. The former group has been presented earlier, and the second study, which includes the proctosigmoidoscopy group, is the basis for this study. Fifty-seven patients undergoing proctosigmoidoscopy were studied. Excluded from the study were patients with fever, diarrhea, inflammatory bowel disease, valvular heart disease, vascular prosthesis, chemotherapy, and immunosuppression. Aerobic and anaerobic blood cultures were taken before, during, and after proctosigmoidoscopy. Additional cultures were taken after a biopsy or polypectomy. Skin cultures were taken from the venipuncture site prior to venipuncture. No bacteremia was demonstrated. Three blood cultures were positive, but all were considered contaminants on the basis of the nature of organisms. No correlates could be drawn as to the depth of insertion, length of time, or position of patient during the procedure. It is concluded that no significant bacteremia occurs during proctosigmoidoscopy. Further studies are warranted in the excluded high-risk group.
为了阐明在下消化道内镜检查期间是否会发生菌血症，开展了两项前瞻性研究，涉及接受结肠镜检查和直肠乙状结肠镜检查的患者。前一组的情况已在之前介绍过，第二项研究（包括直肠乙状结肠镜检查组）是本研究的基础。对57例接受直肠乙状结肠镜检查的患者进行了研究。排除在研究之外的患者包括发热、腹泻、炎症性肠病、心脏瓣膜病、血管假体、化疗和免疫抑制患者。在直肠乙状结肠镜检查前、检查期间和检查后采集需氧和厌氧血培养样本。活检或息肉切除术后还进行了额外的培养。在静脉穿刺前从静脉穿刺部位采集皮肤培养样本。未证实有菌血症。三份血培养呈阳性，但根据微生物的性质，所有这些都被视为污染物。对于操作过程中的插入深度、时间长度或患者体位，无法得出相关性结论。得出的结论是，在直肠乙状结肠镜检查期间不会发生显著的菌血症。有必要对排除在外的高危组进行进一步研究。
