Reinhart W, Hammer B, Sonnabend W
Schweiz Med Wochenschr. 1978 Oct 7;108(40):1545-8.
A prospective study was undertaken to determine the frequency of transient bacteremia on recto-sigmoidoscopy. Blood specimens were drawn for aerobic and anaerobic bacterial culture immediately before, and 1, 5, 10, 15, 20, 25 and 30 min after the beginning of recto-sigmoidoscopy. 19 blood cultures were supposed to be contaminated. In 3 patients (6%) a positive blood culture was found with the following types of organisms: enterococci, Escherichia coli and nonhemolytic streptococci. The need for antibiotic prophylaxis in patients with valvular heart diseases or prosthetic valves is discussed. In such cases the authors propose prophylaxis with 1 g streptomycin i.m. and 3 g ampicillin by mouth 30 min before recto-sigmoidoscopy.
进行了一项前瞻性研究，以确定直肠乙状结肠镜检查时短暂菌血症的发生率。在直肠乙状结肠镜检查开始前以及开始后1、5、10、15、20、25和30分钟，采集血标本进行需氧和厌氧细菌培养。19份血培养被认为受到污染。在3例患者（6%）中，血培养发现阳性，分离出以下类型的微生物：肠球菌、大肠杆菌和非溶血性链球菌。文中讨论了瓣膜性心脏病或人工瓣膜患者使用抗生素预防的必要性。对于此类病例，作者建议在直肠乙状结肠镜检查前30分钟，肌肉注射1g链霉素，口服3g氨苄西林进行预防。
