Martorana G, Giberti C, de Ferrari M, Calvi P, Ottaggio L, Pescatore D
Eur Urol. 1983;9(1):28-31. doi: 10.1159/000474038.
Cytogenetic analysis of resected bladder tumors was performed in 30 patients. None of these patients had previous irradiation or chemotherapy. Direct chromosome preparations were made. Of the 30 preparations, 20 had chromosome abnormalities. We have observed a good correlation between the chromosome abnormalities and the stage/grade of the tumors. Patients were followed from 3 to 23 months. During this period, 61% of the patients with noninvasive or submucosal invasive bladder tumors and chromosome abnormalities have had recurrences. The existence of a good correlation between chromosomal abnormalities and the capacity of the neoplasm to recur was confirmed.
对30例膀胱肿瘤切除标本进行了细胞遗传学分析。这些患者均未接受过放疗或化疗。制备了直接染色体标本。30份标本中，20份存在染色体异常。我们观察到染色体异常与肿瘤分期/分级之间有良好的相关性。对患者进行了3至23个月的随访。在此期间，61%的非浸润性或黏膜下浸润性膀胱肿瘤且有染色体异常的患者出现了复发。证实了染色体异常与肿瘤复发能力之间存在良好的相关性。
