Morrison A S, Jick H, Ory H W
Lancet. 1977 May 28;1(8022):1142-3. doi: 10.1016/s0140-6736(77)92397-2.
History of oral-contraceptive use was compared between 68 women with a hospital-discharge diagnosis of acute hepatitis and 1142 women who had been admitted for other reasons to the same hospitals during the same period. The risk of admission to hospital for hepatitis for users of oral contraceptives was estimated to be 3-3 times that for non-users (95% confidence interval, 1-8--6-3). This overall association was almost entirely attributable to a strong association among women under 25 years of age. Among users of oral contraceptives, duration of use tended to be shorter for hepatitis patients than for controls.
对68例出院诊断为急性肝炎的女性与同期因其他原因入住同一家医院的1142例女性的口服避孕药使用史进行了比较。口服避孕药使用者因肝炎入院的风险估计是非使用者的3.3倍（95%置信区间为1.8至6.3）。这种总体关联几乎完全归因于25岁以下女性中的强关联。在口服避孕药使用者中，肝炎患者的使用时间往往比对照组短。
