Stonestreet B S, Bell E F, Warburton D, Oh W
Am J Dis Child. 1983 Mar;137(3):215-9. doi: 10.1001/archpedi.1983.02140290007002.
Changes in renal function and extracellular fluid volume during the first ten days of life were studied in two groups of low-birth-weight neonates receiving different fluid and sodium intakes from the third to the tenth day. Group 1 neonates received less fluid and sodium and fewer calories than group 2 neonates. Renal function and inulin space were measured before (day 2) and after (day 8) the neonates received the different fluid and sodium managements. Group 2 neonates (on the eight day) had less weight loss, lower plasma sodium and osmolal concentrations, and a similar inulin space per kilogram of body weight as on day 2. Group 1 neonates had more weight loss and a smaller inulin space on day 8 compared with day 2. Low-birth-weight neonates receiving high fluid and sodium loads from days 2 through 8 did not have a contraction of extracellular fluid volume as did those receiving lower fluid and sodium intakes during this period; as a result, the former group had a dilutional decrease in the plasma sodium level and osmolality.
对两组低出生体重新生儿出生后前10天的肾功能和细胞外液容量变化进行了研究，这两组新生儿在出生后第3天至第10天接受不同的液体和钠摄入量。第1组新生儿比第2组新生儿摄入的液体、钠和热量更少。在新生儿接受不同的液体和钠管理之前（第2天）和之后（第8天）测量肾功能和菊粉分布容积。第2组新生儿（第8天）体重减轻较少，血浆钠和渗透压浓度较低，每千克体重的菊粉分布容积与第2天相似。与第2天相比，第1组新生儿在第8天体重减轻更多，菊粉分布容积更小。出生后第2天至第8天接受高液体和钠负荷的低出生体重新生儿，在此期间细胞外液容量没有像接受较低液体和钠摄入量的新生儿那样收缩；结果，前一组血浆钠水平和渗透压出现稀释性降低。
