Roses D F, Snively S L, Phelps R G, Cohen N, Blum M
Am J Surg. 1983 Feb;145(2):266-9. doi: 10.1016/0002-9610(83)90077-6.
Seven patients with carcinoma in a thyroglossal duct cyst have received treatment over a 15 year period. Findings in all of these patients reflect the likelihood of carcinoma arising within thyroglossal duct tissue. In each patient there was sufficient histologic evidence of the presence of a thyroglossal duct cyst and carcinoma arising within an intimate admixture of normal thyroid tissue in the cyst wall. In the absence of a history of irradiation and with separation of the carcinoma from the pyramidal lobe of the thyroid, excision of the thyroglossal cyst alone by traditional means seems appropriate. Our experience as well as a review of reported cases to date indicate that distant metastases are extremely rare and the prognosis excellent.
在15年期间，7例甲状舌管囊肿合并癌患者接受了治疗。所有这些患者的检查结果反映了甲状舌管组织内发生癌变的可能性。每位患者都有足够的组织学证据表明存在甲状舌管囊肿，且囊肿壁内正常甲状腺组织紧密混合处发生了癌变。在没有放疗史且癌灶与甲状腺锥体叶分离的情况下，采用传统方法单独切除甲状舌管囊肿似乎是合适的。我们的经验以及对迄今报道病例的回顾表明，远处转移极为罕见，预后良好。
