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银屑病中的外用类固醇和紫外线辐射。

Topical steroids and UV radiation in psoriasis.

作者信息

Petrozzi J W

出版信息

Arch Dermatol. 1983 Mar;119(3):207-10.

PMID:6824358
Abstract

This study evaluates the benefits of a potent and midstrength topical steroid compared with simple lubricating agents when used in combination with erythemagenic doses of sunlamp fluorescent UV irradiation in psoriasis. Twenty-six patients were studied in a bilateral symmetrical comparison. No significant differences were observed between topical corticosteroids and lubricants in the number of patients achieving a 75% or greater resolution of psoriasis. Topical corticosteroids did not reduce the number of treatments required for clearing. We did not observe faster recurrences in sites treated with topical corticosteroids. More severe burns and slightly less effectiveness were noted in patients irradiated five times weekly compared with three.

摘要

本研究评估了强效和中效外用类固醇与简单润滑剂联合用于红斑剂量的日光灯荧光紫外线照射治疗银屑病时的益处。对26例患者进行了双侧对称比较。在银屑病消退75%或更高的患者数量方面,外用皮质类固醇与润滑剂之间未观察到显著差异。外用皮质类固醇并未减少清除所需的治疗次数。我们未观察到外用皮质类固醇治疗部位复发更快。与每周照射三次的患者相比,每周照射五次的患者出现了更严重的灼伤且疗效略低。

相似文献

1
Topical steroids and UV radiation in psoriasis.银屑病中的外用类固醇和紫外线辐射。
Arch Dermatol. 1983 Mar;119(3):207-10.
2
Double-blind comparison of halcinonide and betamethasone valerate. Use with occlusive dressings in psoriasis treatment.卤米松与戊酸倍他米松的双盲比较。在银屑病治疗中与封闭敷料联合使用。
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Arzneimittelforschung. 1976;26(7b):1499-504.
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[Multicentre-clinical trial of the novel corticosteroid diflucortolone valerate in the forms of cream, ointment and fatty ointment. Part II: Comparative study with several commercial preparations (author's transl)].新型皮质类固醇戊酸二氟可龙乳膏、软膏和脂肪性软膏的多中心临床试验。第二部分:与几种市售制剂的对比研究(作者译)
Arzneimittelforschung. 1976;26(7b):1504-9.
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Topical application of calcipotriene and corticosteroids: combination regimens.卡泊三醇与皮质类固醇的局部应用:联合治疗方案
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Clobetasol propionate followed by calcipotriol is superior to calcipotriol alone in topical treatment of psoriasis.丙酸氯倍他索序贯卡泊三醇在银屑病局部治疗中优于单用卡泊三醇。
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引用本文的文献

1
German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version).德国寻常型银屑病治疗循证指南(简短版)
Arch Dermatol Res. 2007 Jun;299(3):111-38. doi: 10.1007/s00403-007-0744-y. Epub 2007 May 12.
2
Psoriasis. A review of recent advances in treatment.银屑病。治疗新进展综述。
Drugs. 1984 Oct;28(4):324-46. doi: 10.2165/00003495-198428040-00003.