Petrozzi J W
Arch Dermatol. 1983 Mar;119(3):207-10.
This study evaluates the benefits of a potent and midstrength topical steroid compared with simple lubricating agents when used in combination with erythemagenic doses of sunlamp fluorescent UV irradiation in psoriasis. Twenty-six patients were studied in a bilateral symmetrical comparison. No significant differences were observed between topical corticosteroids and lubricants in the number of patients achieving a 75% or greater resolution of psoriasis. Topical corticosteroids did not reduce the number of treatments required for clearing. We did not observe faster recurrences in sites treated with topical corticosteroids. More severe burns and slightly less effectiveness were noted in patients irradiated five times weekly compared with three.
本研究评估了强效和中效外用类固醇与简单润滑剂联合用于红斑剂量的日光灯荧光紫外线照射治疗银屑病时的益处。对26例患者进行了双侧对称比较。在银屑病消退75%或更高的患者数量方面,外用皮质类固醇与润滑剂之间未观察到显著差异。外用皮质类固醇并未减少清除所需的治疗次数。我们未观察到外用皮质类固醇治疗部位复发更快。与每周照射三次的患者相比,每周照射五次的患者出现了更严重的灼伤且疗效略低。