Davies D, Cotton R
Br J Ind Med. 1983 Feb;40(1):22-7. doi: 10.1136/oem.40.1.22.
Two men developed pneumoconiosis after grinding and packing powdered mica. The disease was characterised by progressive dyspnoea, a restrictive impairment of ventilation, a reduced transfer factor, and hypoxaemia. Radiographs showed widespread fine nodular and linear shadows. Progression occurred after cessation of exposure, but this was much more pronounced in the man who died from coronary artery disease. Postmortem examination showed widespread fine fibrosis and nodules measuring up to 1.5 cm in diameter, all related to the deposition of doubly refractile crystals. Mineral formed over 9% of dry tissue weight, and electron microscopy and x-ray analysis showed it to be muscovite. Other minerals were not found.
两名男子在研磨和包装云母粉后患上了尘肺病。该病的特征为进行性呼吸困难、通气受限、转移因子降低和低氧血症。X光片显示有广泛的细小结节和线状阴影。接触停止后病情仍有进展,但在死于冠状动脉疾病的男子身上更为明显。尸检显示有广泛的细纤维化和直径达1.5厘米的结节,均与双折射晶体的沉积有关。矿物质占干组织重量的9%以上,电子显微镜和X射线分析表明其为白云母。未发现其他矿物质。