Block C H, Schwartzbaum J S
Brain Res. 1983 Jan 17;259(1):1-9. doi: 10.1016/0006-8993(83)91061-2.
Neuroanatomical and electrophysiological techniques were used to study efferent projections of the gustatory region of the parabrachial nuclei (PBN) in rabbits. Autoradiographic analysis of [3H]leucine microinjected into electrophysiologically defined gustatory areas of the PBN revealed strong projections to the ventromedial taste component of the ventrobasal complex of the thalamus and also evidence of projections to the lateral hypothalamus, substantia innominata and nucleus centralis amygdala (ACE). Electrical stimulation in the region of ACE was shown to activate antidromically neurons in the PBN responsive to rapid stimuli, confirming gustatory projections to the ventral forebrain. An electrophysiological mapping of units in the amygdala and substantia innominata responsive to electrical stimulation of the gustatory part of the PBN agreed with the autoradiographic data. A proportion of these units were also responsive to gustatory stimuli. However, latencies of evoked response to stimulation of the PBN were unusually long. Outputs from the gustatory PBN to the ventral forebrain may include other modes of polysynaptically integrated information that are largely controlled by interneuronal networks within the PBN.
采用神经解剖学和电生理学技术研究家兔臂旁核（PBN）味觉区的传出投射。对微量注射到经电生理学确定的PBN味觉区的[3H]亮氨酸进行放射自显影分析，结果显示，其向丘脑腹后复合体腹内侧味觉成分发出强投射，同时也有投射至外侧下丘脑、无名质和杏仁中央核（ACE）的证据。结果表明，对ACE区域进行电刺激能逆向激活PBN中对快速刺激有反应的神经元，证实了味觉向腹侧前脑的投射。对杏仁核和无名质中对PBN味觉部分电刺激有反应的单位进行电生理定位，结果与放射自显影数据一致。这些单位中有一部分也对味觉刺激有反应。然而，对PBN刺激诱发反应的潜伏期异常长。从味觉PBN到腹侧前脑的输出可能包括其他多突触整合信息模式，这些模式在很大程度上受PBN内中间神经元网络的控制。
