Kettunen P
Clin Chim Acta. 1983 Jan 7;127(1):97-103. doi: 10.1016/0009-8981(83)90079-7.
The diagnosis of a heart infarct in the early postoperative period is often difficult. In the present study, the levels of serum CK, its isoenzymes (MM, MB and BB), aspartate aminotransferase (ASAT) and alanine aminotransferase (ALAT) were followed up after coronary arteriography (12 patients), cardiac surgery (23 patients) and non-cardiac thoracotomy (28 patients). Elevation of MB was not detected after coronary arteriography, except in two patients, who had had even before the examination a mildly positive MB finding and electrocardiographic changes indicative of subendocardial infarction. After cardiac surgery the MB findings were positive in all but two patients, who had undergone aortic valve surgery. However, the average MB level was lower than in the 10 heart infarct patients who served as controls. After non-cardiac thoracotomy, six patients had a positive serum MB, but the value of MB was quite low as compared with values after cardiac surgery and nearly insignificant in terms of heart infarct diagnosis.
术后早期心肌梗死的诊断往往很困难。在本研究中,对冠状动脉造影(12例患者)、心脏手术(23例患者)和非心脏开胸手术(28例患者)后的血清肌酸激酶(CK)及其同工酶(MM、MB和BB)、天冬氨酸转氨酶(ASAT)和丙氨酸转氨酶(ALAT)水平进行了跟踪。冠状动脉造影后,除两名患者外,未检测到MB升高,这两名患者在检查前MB结果就呈轻度阳性,且心电图有提示心内膜下梗死的改变。心脏手术后,除两名接受主动脉瓣手术的患者外,所有患者的MB结果均为阳性。然而,平均MB水平低于作为对照的10例心肌梗死患者。非心脏开胸手术后,6例患者血清MB呈阳性,但与心脏手术后的值相比,MB值相当低,就心肌梗死诊断而言几乎无意义。